Antigen-Specific Immunotherapy with Thyrotropin Receptor Peptides in Graves’ Hyperthyroidism

Time: 2:30 pm
day: Day Two


  • Apitopes® are designed to mimic naturally processed epitopes to restore the immune system’s natural balance (i.e. tolerance to a self-antigen)
  • ATX-GD-59 is a peptide mixture of two different, highly soluble apitopes® derived from TSH-receptor. Preclinical studies have demonstrated that ATXGD-59 has a significant impact on the anti-TSHR T cell and B cell response
  • A proof of principle study has demonstrated evidence of efficacy in the majority of patients by the reduction of the antibodies and hormones associated with Graves’ disease