Targeting the Thymus to Transform Outcomes in Autoimmune Disease

  • Thymology 101: How the thymus shapes the T cell repertoire by induction of potent and durable Tregs and deletion of autoreactive Tconv cells
  • Zag Bio’s biologics-based approach to target systemically administered antigens to the thymus for restoration of immune homeostasis
  • Demonstration of tissue-specific bystander suppression in autoimmune disease models