Audience Discussion: Examining the Rationale for Combination Therapy Over Monotherapy & Identifying Where Complementary Approaches Could Strengthen Tolerance Induction to Set the Stage for More Durable Antigen-Specific Outcomes
4:30 pm - Wednesday 24th March 2027
- Examining why antigen-specific immune tolerance may need complementary therapies to succeed, to identify where monotherapy alone falls short, and set out where combination approaches could close that gap
- Reviewing which therapies can safely be combined with tolerance induction to distinguish combinations that support the tolerogenic effect from those that interfere with it and build a clearer picture of viable pairing options
- Exploring how depletion-based therapies and tolerance induction could work together, to consider how sequencing or timing might allow one to reinforce the other, and outline a possible framework for combination strategy design
