Measuring the Frequency & Phenotype of Autoreactive T-Cells in Human Blood Samples, to Strengthen How Tolerance is Tracked, & Support More Reliable Monitoring Across Clinical Trials

• Deep profiling of autoreactive T-cells using multiomic single-cell profiling to support treatment efficacy, and demonstrate proof-of-concept, and allow for precise monitoring across clinical trials
• High-throughput analysis of autoreactive T-cells using multiparameter cytokine FLUOROSPOT assays, to enable broader screening of patient samples, and scalable monitoring of trial populations

Speakers:

Tim Tree

Professor of Immune Regulation & Immunotherapy

King's College London