Presenting Mechanistic Mouse Model Data & Top-Line Safety Signals to De-Risk the Path from Preclinical Proof of Mechanism to Patient Outcomes
9:00 am - Thursday 25th March 2027
- Presenting mechanism of action data from mouse models across COUR’s antigenspecific pipeline to show how their nanoparticle platform drives tolerance before a single patient is dosed, giving the field a reproducible template for validating mechanisms ahead of the clinic
- Pairing that mouse model functionality data with preclinical safety results to demonstrate that a blood-based biomarker readout can be functionally linked to disease-altering changes in the target tissue
- Setting out how this mechanistic and safety package informs indication and endpoint selection before trial design begins so the field can learn and avoid costly decisions
